Zanidatamab in HER2-Positive Metastatic Biliary Tract Cancer: Final Results From HERIZON-BTC-0

Shubham Pant; Jia Fan; Do Youn Oh; Hye Jin Choi; Jin Won Kim; Heung Moon Chang; Lequn Bao; Hui Chuan Sun; Teresa Macarulla; Feng Xie; Jean Phillippe Metges; Jie’er Ying; John Bridgewater; Myung Ah Lee; Mohamedtaki A. Tejani; Emerson Y. Chen; Harpreet Wasan; Michel Ducreux; Yuanyuan Bao; Xiaotian Wu; Yi Zhao; Phillip M. Garfin; Jonathon Gable; James J. Harding

doi:10.1001/jamaoncol.2025.4736

Zanidatamab in HER2-Positive Metastatic Biliary Tract Cancer: Final Results From HERIZON-BTC-0

Shubham Pant
, Jia Fan
, Do Youn Oh
, Hye Jin Choi
, Jin Won Kim
, Heung Moon Chang
, Lequn Bao
, Hui Chuan Sun
, Teresa Macarulla
, Feng Xie
, Jean Phillippe Metges
, Jie’er Ying
, John Bridgewater
, Myung Ah Lee
, Mohamedtaki A. Tejani
, Emerson Y. Chen
, Harpreet Wasan
, Michel Ducreux
, Yuanyuan Bao
, Xiaotian Wu

Yi Zhao, Phillip M. Garfin, Jonathon Gable, James J. Harding

Department of Internal Medicine

University of Texas MD Anderson Cancer Center
Zhongshan Hospital
Seoul National University
Yonsei University
University of Ulsan
Hubei Cancer Hospital
Vall d'Hebron Institute of Oncology
Naval Medical University
Hôpital Morvan
Zhejiang Cancer Hospital
University College London
AdventHealth
Oregon Health and Science University
Imperial College Healthcare NHS Trust
Institut Gustave Roussy
BeOne Medicines
Jazz Pharmaceuticals
Memorial Sloan-Kettering Cancer Center
Cornell University

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Original language	English
Pages (from-to)	106-109
Number of pages	4
Journal	JAMA Oncology
Volume	12
Issue number	1
DOIs	https://doi.org/10.1001/jamaoncol.2025.4736
State	Published - 15 Jan 2026

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1001/jamaoncol.2025.4736

Cite this

Pant, S., Fan, J., Oh, D. Y., Choi, H. J., Kim, J. W., Chang, H. M., Bao, L., Sun, H. C., Macarulla, T., Xie, F., Metges, J. P., Ying, J., Bridgewater, J., Lee, M. A., Tejani, M. A., Chen, E. Y., Wasan, H., Ducreux, M., Bao, Y., ... Harding, J. J. (2026). Zanidatamab in HER2-Positive Metastatic Biliary Tract Cancer: Final Results From HERIZON-BTC-0. JAMA Oncology, 12(1), 106-109. https://doi.org/10.1001/jamaoncol.2025.4736

@article{e94f944a6c1c43518a91ced31349210f,

title = "Zanidatamab in HER2-Positive Metastatic Biliary Tract Cancer: Final Results From HERIZON-BTC-0",

author = "Shubham Pant and Jia Fan and Oh, \{Do Youn\} and Choi, \{Hye Jin\} and Kim, \{Jin Won\} and Chang, \{Heung Moon\} and Lequn Bao and Sun, \{Hui Chuan\} and Teresa Macarulla and Feng Xie and Metges, \{Jean Phillippe\} and Jie{\textquoteright}er Ying and John Bridgewater and Lee, \{Myung Ah\} and Tejani, \{Mohamedtaki A.\} and Chen, \{Emerson Y.\} and Harpreet Wasan and Michel Ducreux and Yuanyuan Bao and Xiaotian Wu and Yi Zhao and Garfin, \{Phillip M.\} and Jonathon Gable and Harding, \{James J.\}",

year = "2026",

month = jan,

day = "15",

doi = "10.1001/jamaoncol.2025.4736",

language = "English",

volume = "12",

pages = "106--109",

journal = "JAMA Oncology",

issn = "2374-2437",

publisher = "American Medical Association",

number = "1",

}

Pant, S, Fan, J, Oh, DY, Choi, HJ, Kim, JW, Chang, HM, Bao, L, Sun, HC, Macarulla, T, Xie, F, Metges, JP, Ying, J, Bridgewater, J, Lee, MA, Tejani, MA, Chen, EY, Wasan, H, Ducreux, M, Bao, Y, Wu, X, Zhao, Y, Garfin, PM, Gable, J & Harding, JJ 2026, 'Zanidatamab in HER2-Positive Metastatic Biliary Tract Cancer: Final Results From HERIZON-BTC-0', JAMA Oncology, vol. 12, no. 1, pp. 106-109. https://doi.org/10.1001/jamaoncol.2025.4736

TY - JOUR

T1 - Zanidatamab in HER2-Positive Metastatic Biliary Tract Cancer

T2 - Final Results From HERIZON-BTC-0

AU - Pant, Shubham

AU - Fan, Jia

AU - Oh, Do Youn

AU - Choi, Hye Jin

AU - Kim, Jin Won

AU - Chang, Heung Moon

AU - Bao, Lequn

AU - Sun, Hui Chuan

AU - Macarulla, Teresa

AU - Xie, Feng

AU - Metges, Jean Phillippe

AU - Ying, Jie’er

AU - Bridgewater, John

AU - Lee, Myung Ah

AU - Tejani, Mohamedtaki A.

AU - Chen, Emerson Y.

AU - Wasan, Harpreet

AU - Ducreux, Michel

AU - Bao, Yuanyuan

AU - Wu, Xiaotian

AU - Zhao, Yi

AU - Garfin, Phillip M.

AU - Gable, Jonathon

AU - Harding, James J.

PY - 2026/1/15

Y1 - 2026/1/15

UR - https://www.scopus.com/pages/publications/105023188827

U2 - 10.1001/jamaoncol.2025.4736

DO - 10.1001/jamaoncol.2025.4736

M3 - Article

C2 - 41264278

AN - SCOPUS:105023188827

SN - 2374-2437

VL - 12

SP - 106

EP - 109

JO - JAMA Oncology

JF - JAMA Oncology

IS - 1

ER -

Zanidatamab in HER2-Positive Metastatic Biliary Tract Cancer: Final Results From HERIZON-BTC-0

UN SDGs

Access to Document

Other files and links

Cite this